CM- Rheum -3- SNSA

Question Answer
What are the charachteristics of Seronegative Spondyloarthropathy affects axial skeleton, inflammatory, RF negative, Genetic Predisposition, Enthesopathic, Mucocutaneous Features
name the common spondyloarthropathies Ankylosing spondylitis, Psoriatic Arthritis, Reactive Arthritis, Enteropathic Arthritis (crohns disease, ulcerative colitis), Juvenile Ankylosing Spondylitis
What gene is often associated with spondyloarthropathies but is not necessary or sufficient to cause them HLA-B 27
What are the typical nonvertebral symptoms of spondyloarthropathies Asymmetric Peripheral Arthritis, Arthritis of the toe IP joints, sausage digits, achilles tenosynovitis, plantar fasciitis, costochondritis, Iritis, Mucocutaneous Lesions
What are the major charachteristics of ankylosing spondylitis inflammatory, insidious onset involving vertebra and SI intitially then pepheral joints, you will also have cardiac features 5-10% of the time and Iritis 10-20%. Male>F 4:1 with an age of onset of 15-40
Who suffers from ankylosing spondylitis more 4:1 M>F
When does ankylosing spondylitis usually start ages 15-40
What is the schobers test where you have patient bend when they flex you should go from lordosis to kyphosis. A Person with ankylosing spondylosis will not have any movement in their back as they bend all the movement will come from the hip
What lab findings will you find in ankylosing spondylosis ESR increased 85% of time, RF usually negative, Mild anemai, HLA B27 positive 90%
What x-ray finding is indicative of ankylosing spondylitis Bamboo Spine
What eye finding are common in ankylosing spondylitis inflammation of eye uveitis and iritis when it goes all the way to the limbus
What is the treatment for ankylosing Spondyltiis physical and occupation therapy to maintain posture, exercise (key), stop smoking, NSAIDS, Sulfalsalazine and MTX, Anti-TNF agents
What are the essentials of dx Ankylosing Spondylitis chronic LBP in young adults gen worse in morning, progressive limitation of back motion or chest expansion, transient or permanent arthritis, inflammatory eye disease, elevated ESR, neg RF, HLA-B27, SI ( Sacroiliac Joint) abnormalitis on x-ray
What are the classic characteristics of psoriatic arthritis Nail pitting/onycholysis, inflamm arth DIPs, Asym Arthritis, Sausage digits, no Rheum Nodules, RF -, erosive arthritis w/o osteopenia, Sacroilitis, syndesmophytes, paravert ossification, enthesopathy
What are the patterns of arthritis in psoriatic arthritis DIP arthritis with nail changes, Asymmetirc oligoarthritis, symmetric polyarthritis, asymmetric spondylitsi is possible,
What can be used to manage psoriatic arthritis Topical agents, PUVA, NSAIDs, Methotrexate, leflunomide, sulfasalazine, anti-tnf agents, surgery
What are the essential to dx psoriatic arthritis 80% of time psoriasis before the arthritis, asymmetric sausage appearance of fingers and toes, RF usually neg, SI involvement common with ankylosis, x-ray showing osteolysis, pencil in cup deformity, bony ankylosis, sacroiliitis, syndesmophytes
What is reactive arthritis a seronegative asymmentric arthritis following urethritis or cervicitis or infectious diarrhea.
What conditions are often associated with reactive arthritis enthesopathy (ligament or muscle abnromalities at where they attach to bone), Inflammatory eye disease, balanitis, Oral ulcers, or keratodermia and sacroiliitis
What venereal disease can lead to reactive arthritis chlamydia trichomatis
What enteric diseases can lead to reactive arthritis shigella flexneri, salmonella, yersinia enterocolitica, yersinia pseudotuberculcosis, campylobacter jejuni
What condition can intravesicular bacille calmette-guerin lead to reactive arthritis
What arthritis sometimes presents with keratodermia blenorrhagica Reactive arthritis
What would a clacaneal spur be termed using medico lingo enthesopathy
What is your typical mangement of reactive arthritis include antibiotics, NSAIDs, opthalmic RX, steroids, remittive agents MTX, SSZ, cytotoxic drugs and biologic agents
What are the essential of dx of reactive arthritis 50-89% HLA B-27 +, oligoarthritis, conjunctivitis, urethritis and mouth ulcers are most common, usually follows hx of dysentery or sexually transmitted infection

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